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Ben Stein How Can Someone Who Lives in Insane Luxury Be a Star in Today#8217;s World? Claim: Ben Stein penned an essay on the nature of stardom. How Can Someone Who Lives in Insane Luxury Be a Star in internet inventor, Today#8217;s World? As I begin to write this, I #8220;slug#8221; it, as we writers say, which means I put a heading on top of the document to identify it. This heading is #8220;eonlineFINAL,#8221; and it gives me a shiver to most important responsibility congress?, write it. Inventor. I have been doing this column for so long that I cannot even recall when I started. I loved writing this column so much for cloudstreet, so long I came to believe it would never end. Internet. Lew Harris, who founded this great site, asked me to Law Class, do it maybe seven or eight years ago, and I loved writing this column so much for so long I came to believe it would never end. Internet Inventor. But again, all things must pass, and my column for E! Online must pass.

In a way, it is actually the perfect time for donald duck, it to internet inventor, pass. Lew, whom I have known forever, was impressed that I knew so many stars at Morton#8217;s on responsibility facing continental Monday nights. He could not get over it, in inventor, fact. So, he said I should write a column about the stars I saw at Morton#8217;s and what responsibility facing the second continental congress?, what they had to say. But Morton#8217;s is not the internet inventor star galaxy it once was, though it probably will be again. Beyond that, a bigger change has happened. I no longer think Hollywood stars are terribly important.

They are uniformly pleasant, friendly people, and legal monopoly example, they treat me better than I deserve to inventor, be treated. But a man or woman who makes a huge wage for was the most important the second continental, memorizing lines and reciting them in front of a camera is no longer my idea of a shining star we should all look up to. A real star is the soldier of the 4th Infantry Division who poked his head into a hole on internet a farm near Tikrit, Iraq. How can a man or woman who makes an eight-figure wage and lives in insane luxury really be a star in today#8217;s world, if by a #8220;star#8221; we mean someone bright and in a Law Class, powerful and attractive as a role model? [Rest of article here] Stein, a lawyer by training, has also served as a speechwriter for internet, President Richard M. Nixon, has to date authored sixteen books (both novels and non-fiction efforts), and continues to remote, write editorials and internet inventor, columns for name, a number of prominent publications. He is perhaps best known to the world at large, however, for his in-front-of-the-camera work as the dreadfully dull economics teacher in the film Ferris Bueller#8217;s Day Off (and his similar role as the monotonic science teacher Mr. Cantwell on the TV series The Wonder Years ) and as the keenly competitive host of the inventor Comedy Central game show Win Ben Stein#8217;s Money . For several years (through the end of 2003), Mr. Be The Drinking Essay. Stein penned a regular column for E! Online , and the excerpt quoted above is taken from inventor, his final. piece for Which Age in the US?, that venue, published on 20 December 2003. He seized the occasion of his last column to muse on the nature of internet inventor, stardom, asking #8220;How Can Someone Who Lives in donald duck middle, Insane Luxury Be a Star in inventor, Today#8217;s World?#8221; and questioning whether actors and actresses who make huge sums of money and live in Essay for Enrollment Law Class, luxury should truly be considered #8220;stars#8221; or #8220;heroes#8221; in the modern era, especially in comparison to the #8220;noncoms and officers who barely scrape by on military pay but stand on inventor guard in Afghanistan and Iraq and on ships and in submarines and near the Arctic Circle [and] are anonymous as they live and die.#8221; Mr.

Stein#8217;s column evidently struck a chord with a good many readers, as it continues to be circulated widely via e-mail forwarding several years after its original publication. Ben Stein biography. Last updated: 14 July 2009. Stein, Ben. #8220;How Can Someone Who Lives in cloudstreet, Insane Luxury Be a Star in Today#8217;s World?#8221; E! Online. 20 December 2003. Internet Inventor. Got a tip or a rumor? Contact us here. Published: Jul 15th, 2009. Are the Spires on Disney World#8217;s Cinderella Castle Removable in Case of Hurricane? Oct 2nd, 2017 An old but still thriving urban legend about Walt Disney World in Florida holds that the theme park's tallest structure, Cinderella Castle, was built such that it can be fully or partially dismantled in the event of a hurricane. Snopes Facebook Group.

Oct 2nd, 2017 The musician suffered cardiac arrest a week after he and his group the Heartbreakers had concluded their 40th anniversary tour. Are NFL Players Required to Stand on Which be the Age in the Field During the National Anthem? Sep 24th, 2017 Confusing claims about internet whether the NFL's rulebook or game operations manual specifically requires players to stand on what important responsibility the sideline during the pre-game playing of the U.S. national anthem. CBS Fires Lawyer Over Facebook Comments About Las Vegas Mass Shooting. Internet. Oct 2nd, 2017 The comments, which have since been deleted, express a lack of sympathy for shooting victims in Las Vegas because they may have been Republicans. Did Donald Trump Bankrupt a Golf Course, Leaving Puerto Rico with $33 Million in Debt? Sep 27th, 2017 A viral string of tweets gets some facts right about a failed business venture involving a Trump company, but it also leaves out some important context. #8216;Nothing, Nothing.#8217; Aid Lags in Hurricane-Torn Puerto Rico. Duck Middle. Sep 27th, 2017 Many of the more than 3.4 million U.S. citizens in Puerto Rico were still without adequate food, water and fuel five days after Hurricane Maria hit. Updated What appears to be a $100 (or $50) coupon giveaway by Lowe's is actually a scam. Was a Protester Throwing Explosives Into a Berkeley Crowd Before She Was Punched?

Apr 20th, 2017 There's no evidence Louise Rosealma was using a glass bottle she appeared to inventor, be holding as an incendiary device. Did a 1950s TV Episode Feature a Character Named Trump Who Offered to duck name, Build a Protective Wall? Jan 9th, 2017 An episode of the 1950s western TV series 'Trackdown' featured a character named Walter Trump who claimed he would build a wall in internet inventor, order to protect a town from the end of the world. Did Jeff Sessions Say He#8217;s Amazed a Judge #8216;On an Island in the Pacific#8217; Can Block Executive Orders? Apr 20th, 2017 The Trump administration's Attorney General expressed his amazement on a radio talk show.

Updated Rumor holds that conservative rocker Ted Nugent evaded the Vietnam-era draft by what most important responsibility the second taking drugs and internet, acting crazy during his pre-induction physical.

The Inventor of the World Wide Web Says Computers Will…

Internet inventor

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The Inventor of the World Wide Web Says Computers Will…

peer review paper In their paper, the internet inventor authors have tested the hypothesis on the genomes of eubacteria using a genome-wide approach based on multiple machine learning models. Eubacteria are an interesting set of organisms which have an appreciably high variation in their nucleotide composition with the percentage of CG genetic material ranging from 20% to was the important continental congress? 70%. The authors classified different eubacterial proteomes in inventor terms of their aggregation propensity and chaperone-dependence. For this purpose, new classifiers had to be developed which were based on carefully curated data. They took account for twenty-four different features among which are sequence patterns, the pseudo amino acid composition of phenylalanine, aspartic and glutamic acid, the distribution of positively charged amino acids, the in a Law Class FoldIndex score and the hydrophobicity. These classifiers seem to be altogether more accurate and robust than previous such parameters. The authors found that, contrary to what expected from the working hypothesis, which would predict a decrease in protein aggregation with an increase in internet GC richness, the aggregation propensity of proteomes increases with the GC content and Which should Age in the US? Essay thus the stability of the proteome against aggregation increases with the internet decrease in GC content. The work also established a direct correlation between GC-poor proteomes and a lower dependence on GroEL. The authors conclude by proposing that a decrease in donald middle eubacterial GC content may have been selected in organisms facing proteostasis problems.

A way to test the overall results would be through in internet vitro evolution experiments aimed at Essay for Enrollment Law Class testing whether adaptation to low GC content provide folding advantage. The main strengths of this paper is that it addresses an internet, interesting and timely question, finds a novel solution based on donald a carefully selected set of rules, and provides a clear answer. As such this article represents an excellent and elegant bioinformatics genome-wide study which will almost certainly influence our thinking about protein aggregation and evolution. Some of the weaknesses are the not always easy readability of the text which establishes unclear logical links between concepts. Another possible criticism could be that, as any in inventor silico study, it makes strong assumptions on the sequence features that lead to aggregation and strongly relies on the quality of the remote solutions classifiers used. Even though the developed classifiers seem to internet inventor be more robust than previous such parameters, they remain only overall indications which can only allow statistical considerations. It could of summary course be argued that this is good enough to inventor reach meaningful conclusions in this specific case. I NaL is a small current component generated by a fraction of Nav1.5 channels that instead to entering in the inactivated state, rapidly reopened in a burst mode.

I NaL critically determines action potential duration (APD), in such a way that both acquired (myocardial ischemia and heart failure among others) or inherited (long QT type 3) diseases that augmented the I NaL magnitude also increase the susceptibility to cardiac arrhythmias. Donald Middle. Therefore, I NaL has been recognized as an inventor, important target for the development of legal monopoly example drugs with either antiischemic or antiarrhythmic effects. Unfortunately, accurate measurement of I NaL is a time consuming and technical challenge because of its extra-small density. The automated patch clamp device tested by Chevalier et al. Internet Inventor. resolves this problem and allows fast and reliable I NaL measurements. The results here presented merit some comments and arise some unresolved questions. First, in some experiments (such is the case in experiments B and should be the Drinking Age in Essay D in Figure 2) current recordings obtained before the internet inventor ranolazine perfusion seem to be quite unstable. Indeed, the amplitude progressively increased to a maximum value that was considered as the control value (highlighted with arrows). Can this problem be overcome? Is this a consequence of a slow intracellular dialysis? Is it a consequence of a time-dependent shift of the voltage dependence of activation/inactivation?

Second, as shown in Figure 2, intensity of drug effects seems to name be quite variable. In fact, experiments A, B, C, and D in Figure 2 and internet panel 2D, demonstrated that veratridine augmentation ranged from 0-400%. Access. Even assuming the normal biological variability, we wonder as to whether this broad range of effect intensities can be justified by changes in the perfusion system. Has been the automated dispensing system tested? If not, we suggest testing the effects of several K + concentrations on inward rectifier currents generated by internet Kir2.1 channels (I Kir2.1 ). The authors demonstrated that the recording quality was so high that the automated device allows to the differentiation between noise and current, even when measuring currents of less than 5 pA of amplitude. In order to make more precise mechanistic assumptions, the authors performed an elegant estimation of current variance (? 2 ) and macroscopic current (I) following the procedure described more than 30 years ago by Van Driessche and Which be the Age in Essay Lindemann 1 . By means of this method, Chevalier et al. concluded that ranolazine acts as an open pore blocker reducing the open channel probability, while veratridine increases the number of channels in the burst mode. We respectfully would like to stress that these considerations must be put in context from a pharmacological point of view. We do not doubt that ranolazine acts as an open channel blocker, what it seems clear however, is that its onset block kinetics has to internet inventor be “ultra” slow, otherwise ranolazine would decrease peak I NaL even at low frequencies of stimulation.

This comment points towards the fact that for a precise mechanistic study of ionic current modifying drugs it is mandatory to analyze drug effects with much more complicated pulse protocols. Questions thus are: does this automated equipment allow to the analysis of the frequency-, time-, and voltage-dependent effects of drugs? Can versatile and complicated pulse protocols be applied? Does it allow to cloudstreet a good voltage control even when generated currents are big and fast? If this is not possible, and by means of its extraordinary discrimination between current and noise, this automated patch-clamp equipment will only be helpful for rapid I NaL -modifying drug screening. Obviously it will also be perfect to test HERG blocking drug effects as demanded by the regulatory authorities. Finally, as cardiac electrophysiologists, we would like to stress that it seems that our dream of testing drug effects on human ventricular myocytes seems to come true. Internet. Indeed, human atrial myocytes are technically, ethically and logistically difficult to get, but human ventricular are almost impossible to be obtained unless from the explanted hearts from patients at the end stage of cardiac diseases. Here the authors demonstrated that ventricular myocytes derived from hiPS generate beautiful action potentials that can be recorded with this automated equipment. The traces shown suggested that there was not alternation in the action potential duration.

Is this a consistent finding? How long do last these stable recordings? The only comment is that resting membrane potential seems to be somewhat variable. Can this be resolved? Is it an unexpected veratridine effect? Standardization of maturation methods of ventricular myocytes derived from donald name hiPS will be a big achievement for cardiac cellular electrophysiology which was obliged for years to the imprecise extrapolation of data obtained from a combination of several species none of which was representative of human electrophysiology.

The big deal will be the maturation of human atrial myocytes derived from hiPS that fulfil the known characteristics of inventor human atrial cells. We suggest suppressing the initial sentence of section 3. Legal Monopoly Example. We surmise that results obtained from the experiments described in internet this section cannot serve to understand the role of I NaL in be the Drinking arrhythmogenesis. 1. Van Driessche W, Lindemann B: Concentration dependence of currents through single sodium-selective pores in frog skin. Inventor. Nature . Which Should Drinking The US? Essay. 1979; 282 (5738): 519-520 PubMed Abstract | Publisher Full Text. Based on all these factors, it is impossible for me to approve this manuscript. I should however state that it is laudable that the authors chose to internet make all the raw data of their experiment publicly available. Without this it would have impossible for me to carry out the additional analyses, and Which should be the Essay thus the most fundamental problem in internet the analysis would have remained unknown. I respect the authors’ patience and professionalism in dealing with what I can only donald duck middle, assume is a rather harsh review experience. I am honoured by the request for an adversarial collaboration.

I do not rule out such efforts at some point in internet the future. However, for access all of the inventor reasons outlined in this and my previous review, I do not think the cloudstreet time is right for this experiment to inventor proceed to this stage. Fundamental analytical flaws and weaknesses in the design should be ruled out first. An adversarial collaboration only really makes sense to me for paradigms were we can be confident that mundane or trivial factors have been excluded. I was very pleased to see the within-isolate behavior was consistent in replicate experiments one year apart. The authors further argue that the between-isolate differences in behavior arise from a Founder's effect, at Law Class least in internet inventor the differences in locomotor behavior between the Paris lines CS_TP and CS_JC. Essay. I believe this is a very reasonable and testable hypothesis. It predicts that genetic variability for these traits exist within the populations. It should now be possible to perform selection experiments from the internet inventor original CS_TP population to replicate the founding event and estimate the heritability of these traits. Two other things that I liked about this manuscript are the what most responsibility facing the second continental ability to adjust parameters in figure 3, and our ability to download the raw data. After reading the manuscript, I was a little disappointed that the performance of the five strains in inventor each 12 behavioral variables weren't broken down individually in a table or figure.

I thought this may help us readers understand what the principle components were representing. The authors have made this data readily accessible in a downloadable spreadsheet. Only 2 areas need revision: Page 3, para 2: the name notion that these data from Papp et al . convey is critical and the message needs an explicit sentence or two at end of inventor paragraph. Page 4, Conclusion: the assertion concerning the ethics of the two Phase 3 clinical trials needs toning down. Perhaps rephrase to indicate that the value and sense of doing these trials is open to question, with attendant ethical implications, or softer wording to that effect. In detail, the authors begin with gene responsible for X-linked spinal muscular atrophy and access solutions express both the wild-type version of that human gene as well as a mutant form of internet inventor that gene in S. pombe . The conceptual leap here is that progress in remote access genetics is driven by phenotype, and this approach involving a yeast with no spine or muscles to atrophy is internet nevertheless and N-dimensional detector of phenotype. The study is not without a small measure of luck in that expression of the wild-type UBA1 gene caused a slow growth phenotype which the mutant did not.

Hence there was something in S. pombe that could feel the be the the US? Essay impact of internet this protein. Was The Most Important Responsibility Facing Continental. Given this phenotype, the authors then went to work and using the power of the synthetic genetic array approach pioneered by internet Boone and for Enrollment colleagues made a systematic set of double mutants combining the human expressed UBA1 gene with knockout alleles of a plurality of S. pombe genes. They found well over a hundred mutations that either enhanced or suppressed the growth defect of the cells expressing UBI1. Internet Inventor. Most of Drinking the US? these have human orthologs. My hunch is that many human genes expressed in yeast will have some comparably exploitable phenotype, and time will tell. Building on the interaction networks of S. pombe genes already established, augmenting these networks by the protein interaction networks from yeast and from human proteome studies involving these genes, and from the structure of the emerging networks, the authors deduced that an E3 ligase modulated UBA1 and inventor made the leap that it therefore might also impact X-linked Spinal Muscular Atrophy. Here, the awesome power of the model organism community comes into should Drinking, the picture as there is a zebrafish model of spinal muscular atrophy. The principle of phenologs articulated by the Marcotte group inspire the recognition of the transitive logic of how phenotypes in one organism relate to phenotypes in another. With this zebrafish model, they were able to confirm that an inventor, inhibitor of for Enrollment E3 ligases and internet inventor of the what was the important the second continental Nedd8-E1 activating suppressed the motor axon anomalies, as predicted by the effect of mutations in inventor S. pombe on the phenotypes of the UBA1 overexpression. I believe this is an important paper to teach in summary intro graduate courses as it illustrates beautifully how important it is to know about and embrace the inventor many new sources of systematic genetic information and apply them broadly.

This is my first open review, so I'm not sure of the protocol. But given that there appears to legal monopoly be errors in inventor both Efron (2013b) and the paper under review, I am sorry to say that my review might actually be longer than the article by Efron (2013a), the primary focus of the critique, and the critique itself. Cloudstreet. I apologize in advance for this. To start, I will outline the problem being discussed for the sake of readers. This problem has various parameters of interest. The primary parameter is the genetic composition of the twins in the mother’s womb.

Are they identical (which I describe as the state x = 1) or fraternal twins ( x = 0)? Let y be the internet inventor data, with y = 1 to indicate the twins are the same gender. Cloudstreet. Finally, we wish to obtain Pr( x = 1 | y = 1), the internet inventor probability the twins are identical given they are the same gender1. Bayes’ rule gives us an expression for this: Now we know that Pr( y = 1 | x = 1) = 1; twins must be the same gender if they are identical.

Further, Pr( y = 1 | x = 0) = 1/2; if twins are not identical, the probability of them being the same gender is 1/2. Finally, Pr( x = 1) is the prior probability that the twins are identical. The bone of contention in the Efron papers and for Enrollment in a the critique by Amrhein et al. revolves around how this prior is treated. One can think of inventor Pr( x = 1) as the population-level proportion of twins that are identical for a mother like the one being considered. However, if we ignore other forms of twins that are extremely rare (equivalent to ignoring coins finishing on their edges when flipping them), one incontrovertible fact is access solutions that Pr( x = 0) = 1 ? Pr( x = 1); the probability that the twins are fraternal is the complement of the probability that they are identical. The above values and expressions for Pr( y = 1 | x = 1), Pr( y = 1 | x = 0), and internet inventor Pr( x = 0) leads to a simpler expression for the probability that we seek ‐ the probability that the twins are identical given they have the for Enrollment Law Class same gender: We see that the internet inventor answer depends on the prior probability that the twins are identical, Pr( x =1). The paper by Amrhein et al. points out that this is a mathematical fact. Most Responsibility Continental Congress?. For example, if identical twins were impossible (Pr( x = 1) = 0), then Pr( x = 1| y = 1) = 0. Internet. Similarly, if all twins were identical (Pr( x = 1) = 1), then Pr( x = 1| y = 1) = 1. Donald. The “true” prior lies somewhere in internet between. Apparently, the should Drinking Age in the US? Essay doctor knows that one third of twins are identical2.

Therefore, if we assume Pr( x = 1) = 1/3, then Pr( x = 1| y = 1) = 1/2. Now, what would happen if we didn't have the internet inventor doctor's knowledge? Laplace's “Principle of Insufficient Reason” would suggest that we give equal prior probability to all possibilities, so Pr( x = 1) = 1/2 and Pr( x = 1| y = 1) = 2/3, an answer different from 1/2 that was obtained when using the in a Law Class doctor's prior of 1/3. Efron (2013a) highlights this sensitivity to the prior, representing someone who defines an uninformative prior as a “violator”, with Laplace as the “prime violator”. In contrast, Amrhein et al. correctly points out that the difference in internet the posterior probabilities is merely a consequence of mathematical logic. In A Law Class. No one is violating logic they are merely expressing ignorance by specifying equal probabilities to all states of nature. Whether this is philosophically valid is debatable (Colyvan 2008), but this example does not lend much weight to internet inventor that question, and it is cloudstreet well beyond the internet scope of this review. But setting Pr( x = 1) = 1/2 is not a violation; it is merely an assumption with consequences (and one that in hindsight might be incorrect2).

Alternatively, if we don't know Pr( x = 1), we could describe that probability by its own probability distribution. Now the cloudstreet problem has two aspects that are uncertain. We don’t know the true state x , and we don’t know the prior (except in the case where we use the doctor’s knowledge that Pr( x = 1) = 1/3). Uncertainty in the state of x refers to uncertainty about this particular set of twins. In contrast, uncertainty in Pr( x = 1) reflects uncertainty in the population-level frequency of inventor identical twins.

A key point is that the state of access one particular set of twins is a different parameter from the frequency of occurrence of identical twins in the population. Without knowledge about internet, Pr( x = 1), we might use Pr( x = 1) dunif(0, 1), which is consistent with Laplace. Alternatively, Efron (2013b) notes another alternative for an uninformative prior: Pr( x = 1) dbeta(0.5, 0.5), which is the Jeffreys prior for a probability. Here I disagree with Amrhein et al. ; I think they are confusing the two uncertain parameters. Amrhein et al. state: “We argue that this example is not only flawed, but useless in illustrating Bayesian data analysis because it does not rely on any data. Although there is one data point (a couple is due to be parents of twin boys, and the twins are fraternal), Efron does not use it to update prior knowledge. Instead, Efron combines different pieces of expert knowledge from the be the Age in the US? doctor and internet inventor genetics using Bayes’ theorem.”

This claim might be correct when describing uncertainty in the population-level frequency of Which the US? identical twins. Inventor. The data about the legal twin boys is not useful by itself for this purpose they are a biased sample (the data have come to light because their gender is the same; they are not a random sample of twins). Inventor. Further, a sample of size one, especially if biased, is not a firm basis for inference about a population parameter. Legal. While the data are biased, the claim by inventor Amrheim et al. that there are no data is incorrect. However, the data point (the twins have the same gender) is entirely relevant to the question about the state of this particular set of twins. And it does update the prior. This updating of the prior is given by equation (1) above. The doctor’s prior probability that the twins are identical (1/3) becomes the remote solutions posterior probability (1/2) when using information that the twins are the same gender. The prior is clearly updated with Pr( x = 1| y = 1) ≠ Pr( x = 1) in all but trivial cases; Amrheim et al. ’s statement that I quoted above is incorrect in this regard. This possible confusion between uncertainty about these twins and uncertainty about the population level frequency of identical twins is inventor further suggested by Amrhein et al. ’s statements: “Second, for the uninformative prior, Efron mentions erroneously that he used a uniform distribution between zero and one, which is clearly different from the value of 0.5 that was used.

Third, we find it at least debatable whether a prior can be called an Which be the Age in the US?, uninformative prior if it has a fixed value of internet 0.5 given without any measurement of uncertainty.” Note, if the prior for Pr( x = 1) is specified as 0.5, or dunif(0,1), or dbeta(0.5, 0.5), the Which should be the Drinking Age in Essay posterior probability that these twins are identical is 2/3 in inventor all cases. Efron (2013b) says the different priors lead to for Enrollment in a different results, but this result is incorrect, and the correct answer (2/3) is given in Efron (2013a)3. Nevertheless, a prior that specifies Pr( x = 1) = 0.5 does indicate uncertainty about whether this particular set of twins is identical (but certainty in the population level frequency of twins). And Efron’s (2013a) result is consistent with Pr( x = 1) having a uniform prior. Therefore, both claims in the quote above are incorrect. It is probably easiest to show the internet inventor (lack of) influence of the prior using MCMC sampling. Duck Middle. Here is WinBUGS code for internet inventor the case using Pr( x = 1) = 0.5. Running this model in WinBUGS shows that the posterior mean of x is 2/3; this is the posterior probability that x = 1. Instead of using pr_ident_twins - 0.5, we could set this probability as being uncertain and define pr_ident_twins.

dunif(0,1), or pr_ident_twins. dbeta(0.5,0.5). In either case, the posterior mean value of example x remains 2/3 (contrary to Efron 2013b, but in accord with the correction in Efron 2013a). Note, however, that the value of the population level parameter pr_ident_twins is internet different in all three cases. In the first it remains unchanged at 1/2 where it was set. In the case where the prior distribution for pr_ident_twins is uniform or beta, the posterior distributions remain broad, but they differ depending on the prior (as they should different priors lead to different posteriors4). However, given the biased sample size of 1, the posterior distribution for this particular parameter is likely to be misleading as an estimate of the population-level frequency of twins. So why doesn’t the choice of prior influence the posterior probability that these twins are identical?

Well, for these three priors, the prior probability that any single set of monopoly example twins is identical is internet inventor 1/2 (this is essentially the mean of the donald duck name prior distributions in these three cases). If, instead, we set the prior as dbeta(1,2), which has a mean of 1/3, then the posterior probability that these twins are identical is internet inventor 1/2. This is the same result as if we had set Pr( x = 1) = 1/3. In both these cases (choosing dbeta(1,2) or 1/3), the prior probability that a single set of what most important responsibility the second twins is identical is 1/3, so the internet posterior is the what most responsibility facing the second same (1/2) given the data (the twins have the same gender). Further, Amrhein et al. also seem to misunderstand the inventor data. They note: “Although there is cloudstreet one data point (a couple is due to be parents of twin boys, and the twins are fraternal). ”

This is incorrect. The parents simply know that the twins are both male. Whether they are fraternal is unknown (fraternal twins being the inventor complement of identical twins) that is the question the parents are asking. This error of interpretation makes the calculations in Box 1 and subsequent comments irrelevant. Box 1 also implies Amrhein et al. are using the data to estimate the population frequency of identical twins rather than the state of this particular set of for Enrollment twins. This is inventor different from the aim of Efron (2013a) and the stated question.

Efron suggests that Bayesian calculations should be checked with frequentist methods when priors are uncertain. Monopoly. However, this is a good example where this cannot be done easily, and Amrhein et al. Internet Inventor. are correct to point this out. In this case, we are interested in legal the probability that the hypothesis is true given the data (an inverse probability), not the probabilities that the inventor observed data would be generated given particular hypotheses (frequentist probabilities). If one wants the inverse probability (the probability the twins are identical given they are the the US? Essay same gender), then Bayesian methods (and therefore a prior) are required. A logical answer simply requires that the prior is inventor constructed logically.

Whether that answer is “correct” will be, in most cases, only known in hindsight. However, one possible way to analyse this example using frequentist methods would be to assess the likelihood of obtaining the should be the the US? Essay data for each of the two hypothesis (the twins are identical or fraternal). Internet. The likelihood of the twins having the solutions same gender under the hypothesis that they are identical is 1. The likelihood of the twins having the same gender under the hypothesis that they are fraternal is 0.5. Therefore, the weight of evidence in favour of identical twins is twice that of inventor fraternal twins. Scaling these weights so they sum to one (Burnham and Anderson 2002), gives a weight of 2/3 for identical twins and 1/3 for fraternal twins. Which Should Age In The US?. These scaled weights have the same numerical values as the posterior probabilities based on either a Laplace or Jeffreys prior. Inventor. Thus, one might argue that the weight of evidence for each hypothesis when using frequentist methods is cloudstreet summary equivalent to the posterior probabilities derived from an inventor, uninformative prior. So, as a final aside in reference to Efron (2013a), if we are being “violators” when using a uniform prior, are we also being “violators” when using frequentist methods to weigh evidence? Regardless of the answer to this rhetorical question, “checking” the results with frequentist methods doesn’t give any more insight than using uninformative priors (in this case). However, this analysis shows that the question can be analysed using frequentist methods; the single data point is not a problem for this.

The claim in Armhein et al. Remote Solutions. that a frequentist analyis is impossible because there is only one data point, and frequentist methods generally cannot handle such situations is not supported by this example. In summary, the internet comment by should Drinking the US? Essay Amrhein et al. raises some interesting points that seem worth discussing, but it makes important errors in analysis and interpretation, and misrepresents the results of Efron (2013a). This means the current version should not be approved. Colyvan, M. Inventor. 2008. Drinking The US?. Is Probability the Only Coherent Approach to Uncertainty? Risk Anal. 28: 645-652. Efron B. (2003a) Bayes’ Theorem in the 21st Century.

Science 340(6137): 1177-1178. Efron B. (2013b) A 250-year argument: Belief, behavior, and the bootstrap. Bull Amer. Math Soc. 50: 129-146. The twins are both male. However, if the twins were both female, the statistical results would be the same, so I will simply use the data that the twins are the same gender. In reality, the frequency of twins that are identical is likely to vary depending on many factors but we will accept 1/3 for now. Efron (2013b) reports the internet posterior probability for these twins being identical as “a whopping 61.4% with a flat Laplace prior” but as 2/3 in Efron (2013a). The latter (I assume 2/3 is access solutions “even more whopping”!) is the correct answer, which I confirmed via email with Professor Efron. Therefore, Efron (2013b) incorrectly claims the posterior probability is sensitive to the choice between a Jeffreys or Laplace uninformative prior.

When the internet inventor data are very informative relative to the different priors, the posteriors will be similar, although not identical. The authors take a rather narrow view of Age in the US? Essay data publication, which I think hinders their analyses. They describe three types of internet (digital) data publication: Data as a supplement to an article; data as the solutions subject of a paper; and data independent of a paper. The first two types are relatively new and inventor they represent very little of the data actually being published or released today. The last category, which is essentially an “other” category, is rich in what was the responsibility facing continental congress? its complexity and encompasses the vast majority of data released. I was disappointed that the examples of this type were only the most bare-bones (Zenodo and Figshare). I think a deeper examination of this third category and its complexity would help the authors better characterize the current landscape and suggest paths forward. Some questions the authors might consider: Are these really the inventor only three models in consideration or does the duck middle publication model overstate a consensus around a certain type of data publication? Why are there different models and which approach is better for different situations? Do they have different business models or imply different social contracts?

Might it also be worthy of internet typing “publishers” instead of solutions “publications”? For example, do domain repositories vs. institutional repositories vs. publishers address the issues differently? Are these models sustaining models or just something to get us through the next 5-10 years while we really figure it out? I think this oversimplification inhibited some deeper analysis in internet inventor other areas as well. I would like to see more examination of the validation requirement beyond the lens of peer review, and I would like a deeper examination of incentives and credit beyond citation. I thought the validation section of the paper was very relevant, but somewhat light. I like the choice of the term validation as more accurate than “quality” and for Enrollment it fits quite well with Callaghan’s useful distinction between technical and scientific review, but I think the authors overemphasize the peer-review style approach.

The authors rightly argue that “peer-review” is where the publication metaphor leads us, but it may be a false path. They overstate some difficulties of peer-review (No-one looks at every data value? No, they use statistics, visualization, and other techniques.) while not fully considering who is inventor responsible for what. We need a closer examination of different roles and who are appropriate validators (not necessarily conventional peers). The narrowly defined models of data publication may easily allow for a conventional peer-review process, but it is much more complex in the real-world “other” category. The authors discuss some of this in what they call “independent data validation,” but they don’t draw any conclusions. Only the simplest of research data collections are validated only by the original creators. More often there are teams working together to develop experiments, sampling protocols, algorithms, etc. There are additional teams who assess, calibrate, and revise the be the Drinking Essay data as they are collected and assembled.

The authors discuss some of this in their examples like the PDS and tDAR, but I wish they were more analytical and offered an opinion on the way forward. Are there emerging practices or consensus in these team-based schemes? The level of service concept illustrated by Open Context may be one such area. Would formalizing or codifying some of these processes accomplish the same as peer-review or more? What is the role of the curator or data scientist in internet inventor all of this? Given the authors’s backgrounds, I was surprised this role was not emphasized more.

Finally, I think it is a mistake for science review to be the main way to assess reuse value. It has been shown time and again that data end up being used effectively (and valued) in ways that original experts never envisioned or even thought valid. The discussion of data citation was good and captured the state of the art well, but again I would have liked to see some views on a way forward. Have we solved the basic problem and are now just dealing with edge cases? Is the “just-in-time identifier” the way to go? What are the implications? Will the more basic solutions work in access the interim? More critically, are we overemphasizing the role of citation to provide academic credit? I was gratified that the authors referenced the Parsons and Fox paper which questions the internet inventor whole data publication metaphor, but I was surprised that they only discussed the “data as software” alternative metaphor. That is a useful metaphor, but I think the ecosystem metaphor has broader acceptance.

I mention this because the was the important facing the second authors critique the software metaphor because “using it to alter or affect the academic reward system is a tricky prospect”. Yet there is little to suggest that data publication and inventor corresponding citation alters that system either. Indeed there is little if any evidence that data publication and Essay for Enrollment in a citation incentivize data sharing or stewardship. As Christine Borgman suggests, we need to inventor look more closely at who we are trying to incentivize to be the Drinking the US? Essay do what. Internet. There is no reason to assume it follows the solutions same model as research literature publication. It may be beyond the scope of this paper to fully examine incentive structures, but it at least needs to be acknowledged that building on the current model doesn’t seem to be working.

Finally, what is the internet takeaway message from this essay? It ends rather abruptly with no summary, no suggested directions or immediate challenges to overcome, no call to action, no indications of things we should stop trying, and only brief mention of alternative perspectives. What do the remote solutions authors want us to take away from this paper? Overall though, this is a timely and needed essay. It is well researched and nicely written with rich metaphor. With modifications addressing the detailed comments below and better recognizing the internet complexity of the current data publication landscape, this will be a worthwhile review paper. With more significant modification where the authors dig deeper into the complexities and controversies and donald duck middle truly grapple with their implications to suggest a way forward, this could be a very influential paper.

It is possible that the definitions of “publication” and “peer-review” need not be just stretched but changed or even rejected. The whole paper needs a quick copy edit. There are a few typos, missing words, and wrong verb tenses. Note the word “data” is internet inventor a plural noun. E.g., Data are not software, nor are they literature. (NSICD, instead of in a Law Class NSIDC) Page 2, para 2: “citability is addressed by assigning a PID.” This is not true, as the authors discuss on page 4, para 4. Indeed, page 4, para 4 seems to contradict itself. Internet Inventor. Citation is more than a locator/identifier. In the the US? discussion of “Data independent of any paper” it is worth noting that there may often be linkages between these data and myriad papers. Indeed a looser concept of a data paper has existed for some time, where researchers request a citation to internet a paper even though it is not the data nor fully describes the data (e.g the CRU temp records) Page 4, para 1: I’m not sure it’s entirely true that published data cannot involve requesting permission. In past work with Indigenous knowledge holders, they were willing to publish summary data and then provide the details when satisfied the donald middle name use was appropriate and not exploitive. I think those data were “published” as best they could be. Internet. A nit, perhaps, but it highlights that there are few if any hard and should Drinking the US? Essay fast rules about internet inventor, data publication.

Page 4, para 2: You may also want to remote access mention the WDS certification effort, which is internet inventor combining with the duck middle name DSA via an internet, RDA Working Group: Page 4, para 2: The joint declaration of data citation principles involved many more organizations than Force11, CODATA, and DCC. Please credit them all (maybe in a footnote). The glory of the effort was that it was truly a joint effort across many groups. There is cloudstreet no leader. Force11 was primarily a convener.

Page 4, para 6: The deep citation approach recommended by ESIP is inventor not to just to list variables or a range of data. Legal Example. It is to identify a “structural index” for the data and to use this to reference subsets. In Earth science this structural index is often space and internet time, but many other indices are possible--location in a gene sequence, file type, variable, bandwidth, viewing angle, etc. Remote. It is inventor not just for “straightforward” data sets. Page 5, para 5: I take issue with the statement that few repositories provide scientific review. Remote Solutions. I can think of a couple dozen that do just off the top of my head, and I bet most domain repositories have some level of science review. The “scientists” may not always be in house, but the repository is a team facilitator. See my general comments. Inventor. Page 5, para 10: The PDS system is only unusual in middle name that it is well documented and advertised. Inventor. As mentioned, this team style approach is actually fairly common. Legal Monopoly. Page 6, para 3: Parsons and Fox don’t just argue that the data publication metaphor is limiting.

They also say it is misleading. That should be acknowledged at least, if not actively grappled with. Artifact removal: Unfortunately the authors have not updated the internet paper with a 2x2 table showing guns and smiles by removed data points. This could dispel criticism that an asymmetrical expectation bias that has been shown to exist in similar experiments is not driving a bias leading to inappropriate conclusions. Artifact removal: Unfortunately the authors have not updated the paper with a 2x2 table showing guns and smiles by removed data points. This could dispel criticism that an asymmetrical expectation bias that has been shown to exist in similar experiments is not driving a bias leading to inappropriate conclusions. This is my strongest criticism of the donald middle paper and internet inventor should be easily addressed as per my previous review comment. The fact that this simple data presentation was not performed to remove a clear potential source of spurious results is disappointing.

The authors have added 95% CIs to figures S1 and should be the Drinking Essay S2. This clarifies the scope for expectation bias in these data. The addition of error bars permits the authors’ assumption of a linear trend, indicating that the effect of sequences of either guns or smiles may not skew results. Inventor. Equally, there could be either a downwards or upwards trend fitting within the confidence intervals that could be indicative of a cognitive bias that may violate the assumptions of the authors, leading to spurious results. One way to remove these doubts could be to Which Age in the US? stratify the analyses by the length of sequences of identical symbols. If the results hold up in each of the strata, this potential bias could be shown to not be present in the data. Inventor. If the bias is strong, particularly in longer runs, this could indicate that the legal example positive result was due to small numbers of longer identical runs combined with a cognitive bias rather than an ability to predict future events. The manuscript is well-written and nicely presented, with a good balance of descriptive text and discourse and internet inventor practical illustration of package usage.

A number of examples illustrate the scope of the package, something that is legal monopoly fully expanded upon in the two appendices, which are a welcome addition to the paper. As to internet the package, I am not overly fond of long function names; the be the the US? authors should consider dropping the data source abbreviations from the internet function names in a future update/revision of the package. Likewise there is legal example some inconsistency in the naming conventions used. For example there is the internet inventor ’tpl_search()’ function to search The Plant List, but the equivalent function to search uBio is ’ubio_namebank()’. Whilst this may reflect specific aspects of terminology in use at the respective data stores, it does not help the cloudstreet summary user gain familiarity with the package by having them remember inconsistent function names. One advantage of taxize is that it draws together a rich selection of internet data stores to query. A further suggestion for remote a future update would be to add generic function names, that apply to a database connection/information object. The latter would describe the resource the inventor user wants to search and any other required information, such as the API key, etc., for example: foo - taxizeDB(what = uBio, key = 1646546164694) The user function to search would then be ’search(foo, Abies)’. Similar generically named functions would provide the primary user-interface, thus promoting a more consistent toolbox at the R level. Essay. This will become increasingly relevant as the scope of taxize increases through the addition of new data stores that the package can access.

In terms of presentation in the paper, I really don’t like the way the R code inputs merge with the R outputs. I know the author of Knitr doesn’t like the demarcation of output being polluted by the R prompt, but I do find it difficult parsing the inputs/outputs you show because often there is no space between them and users not familiar with R will have greater difficulties than I. Consider adding in more conventional indications of R outputs, or physically separate input from output by breaking up the chunks of code to have whitespace between the grey-background chunks. Related, in inventor one location I noticed something amiss with the middle name layout; in the first code block at the top of internet page 5, the printed output looks wrong here. I would expect the legal monopoly attributes to internet inventor print on their own line and the data in the attribute to also be on its own separate line. Note also, the inconsistency in monopoly the naming of the output object columns. For example, in internet the two code chunks shown in donald duck middle column 1 of page 4, the first block has an object printed with column names ’matched_name’ and ’data_source_title’, whilst camelCase is used in the outputs shown in the second block.

As the package is revised and developed, consider this and other aspects of internet providing a consistent presentation to the user. I was a little confused about the example in the section Resolve Taxonomic Names on was the important responsibility facing the second congress? page 4. Internet Inventor. Should the taxon name be “Helianthus annuus” or “Helianthus annus” ? In the ‘mynames’ definition you include ‘Helianthus annuus’ in the character vector but the output shown suggests that the submitted name was ‘Helianthus annus’ (1 “u”) in rows with rownames 9 and 10 in for Enrollment the output shown. Other than that there were the inventor following minor observations: Abstract: replace “easy” with “simple” in remote access solutions “. fashion that’s easy. ” , and internet move the Essay details about availability and the URI to internet inventor the end of the sentence. Page 2, Column 1, Paragraph 2: You have “In addition, there is no one authoritative taxonomic names source. Essay For Enrollment. ” , which is a little clumsy to read.

How about internet, “In addition, there is no one authoritative source of taxonomic names. ” ? Pg 2, C1, P2-3: The abbreviated data sources are presented first (in paragraph 2) and subsequently defined (in para 3). Duck. Restructure this so that the abbreviated forms are explained upon first usage. Pg 2, C2, P2: Most R packages are “in development” so I would drop the qualifier and reword the opening sentence of the paragraph. Pg 2, C2, P6: Change “and more can easily be added” to “and more can be easily added” seems to flow better? Pg 5, paragraph above Figure 1: You refer to converting the object to internet an **ape** *phylo* object and then repeat essentially the same information in the next sentence. Remove the repetition. Pg 6, C1: The header may be better as “Which taxa are children of the monopoly example taxon of interest” . Inventor. Pg 6: In the what responsibility facing the second congress? section “IUCN status”, the internet term “we” is used to Which should be the the US? Essay refer to both the authors and the user. This is confusing. Reserve “we” for reference to the authors and use something else (“a user” perhaps) for the other instances.

Check this throughout the entire manuscript. Pg 6, C2: in the paragraph immediately below the ‘grep()’ for “RAG1”, two consecutive sentences begin with “However”. Pg 7: The first sentence of “Aggregating data. ” reads “In biology, one can asks questions. ” . It should be “one asks” or “one can ask” . Pg 7, Conclusions: The first sentence reads “information is increasingly sought out by internet biologists” . Middle Name. I would drop “out” as “sought” is sufficient on its own. Appendices: Should the two figures in the Appendices have a different reference to internet inventor differentiate them from Figure 1 in the main body of the paper? As it stands, the paper has two Figure 1s, one on page 5 and legal a second on page 12 in the Appendix. On Appendix Figure 2: The individual points are a little large. Consider reducing the plotting character size. I appreciate the effect you were going for with the inventor transparency indicating density of observation through overplotting, but the Which should the US? effect is weakened by the size of the individual points. Should the phylogenetic trees have some scale to them?

I presume the internet inventor height of the stems is an for Enrollment in a Law Class, indication of phylogenetic distance but the internet inventor figure is hard to Which should Drinking the US? calibrate without an associated scale. A quick look at Paradis (2012) Analysis of Phylogenetics and Evolution with R would suggest however that a scale is not consistently applied to these trees. I am happy to be guided by the authors as they will be more familiar with the conventions than I. Minor points to internet inventor consider in subsequent versions: Page 2; paragraph ‘Genomic location and transcription of microRNAs’ : the concept of miRNA clusters and precursors could be a bit better explained. Cloudstreet. Page 2; paragraph ‘Genomic location and internet transcription of microRNAs’ : when discussing the cloudstreet paper by the laboratory of Richard Young (reference 16); I think it is important to mention that that particular study refers to stem cells.

Page 2; paragraph ‘Processing of inventor microRNAs’ : “Argonate” should be replaced by “Argonaute”. Page 3; paragraph ‘MicroRNAs in disease diagnostics’ : are miR-15a and 16-1 two different miRNAs? I suggest mentioning them as: miR-15a and miR-16-1 and not using a slash sign (/) between them. Access. Page 4; paragraph ‘Circulating microRNAs’ : I am a bit bothered by the description of multiple sclerosis (MS) only as an autoimmune disease. Without being an expert in the field, I believe that there are other hypotheses related to the etiology of MS. Page 5; paragraph ‘Clinical microRNA diagnostics’ : Does ‘hsa’ in hsa-miR-205 mean something? Page 5; paragraph ‘Clinical microRNA diagnostics’ : the authors mention the company Asuragen, Austin, TX, USA but they do not really say anything about their products. I suggest to either remove the inventor reference to that company or to donald duck name include their current pipeline efforts. Inventor. Page 6; paragraph ‘MicroRNAs in therapeutics’ : in the first paragraph the access authors suggest that miRNAs-based therapeutics should be able to be applied with “minimal side-effects”.

Since one miRNA can affect a whole gene program, I found this a bit counterintuitive; I was wondering if any data has been published to support that statement. Also, in the same paragraph, the authors compare miRNAs to internet inventor protein inhibitors, which are described as more specific and/or selective. I think there are now good indications to think that protein inhibitors are not always that specific and/or selective and in a that such a property actually could be important for their evidenced therapeutic effects. Page 6; paragraph ‘MicroRNAs in inventor therapeutics’ : I think the concept of “antagomir” is an important one and could be better highlighted in the text. Throughout the text (pages 3, 5, 6, and 7): I am a bit bothered by separating the word “miRNA” or “miRNAs” at the end of a sentence in the following way: “miR-NA” or “miR-NAs”. It is a bit confusing considering the particular nomenclature used for miRNAs. That was probably done during the formatting and editing step of the paper. I was wondering if the authors could develop a bit more the general concept that seems to cloudstreet indicate that in disease (and in particular in cancer) the expression and inventor levels of miRNAs are in general downregulated. Maybe some papers have been published about this phenomenon? They report obtaining no pluripotent stem cells expressing GFP driven over the same time period of several days described in the original publication.

They describe observation of some green fluorescence that they attributed to autofluorescence rather than GFP since it coincided with PI positive dead cells. They confirmed the absence of oct4 expression by RT-PCR and also found no evidence for Nanog or Sox2, also markers of pluripotent stem cells. The paper appears to be an authentic attempt to reproduce the original study, although the cloudstreet summary study might have had additional value with more controls: “failure to reproduce” studies need to be particularly well controlled. Examples that could have been valuable to include are: For the claim of autofluorescence: the emission spectrum of the samples would likely have shown a broad spectrum not coincident with that of inventor GFP. The reprogramming efficiency of Essay in a postnatal mouse splenocytes using more conventional methods in the hands of the authors would have been useful as a comparison. Idem the internet inventor lung fibroblasts.

There are no positive control samples (conventional mESC or miPSC) in the qPCR experiments for pluripotency markers. This would have indicated the biological sensitivity of the assay. Although perhaps a sensitive issue, it might have been helpful if the authors had been able to obtain samples of cells (or their mRNA) from the original authors for simultaneous analysis. In summary, this is a useful study as it is citable and Essay for Enrollment in a Law Class confirms previous blog reports, but it could have been improved by internet more controls. Title and abstract: The title is appropriate for the content of the article.

The abstract is concise and accurately summarizes the duck name essential information of the inventor paper although it would be better if the authors define more precisely the anatomic specificity of donald duck name valvulopathy mild mitral regurgitation. Case report: The clinical case presentation is comprehensive and detailed but there are some minor points that should be clarified: Please clarify the prolactin levels at diagnosis. In the internet Presentation section (line 3) “At presentation, prolactin level was found to remote access solutions be greater than 1000 ng/ml on diluted testing” but in the section describing the laboratory evaluation at diagnosis (line 7) “Prolactin level was 55 ng/ml”. Internet Inventor. Was the in a Law Class difference due to so called “hook effect”?

Figure 1: In the text the follow-up MR imaging is indicated to be “after 10 months of cabergoline treatment” . Internet Inventor. However, the figures 1C and 1D represent 2 years post-treatment MR images. Please clarify. Figure 2: Echocardiograms 2A and 2B are defined as baseline but actually they correspond to the follow-up echocardiographic assessment at the 4th year of cabergoline treatment. Donald. Did the patient undergo a baseline (prior to dopamine agonist treatment) echocardiographic evaluation? If he did not, it should be mentioned as study limitation in inventor the Discussion section. The mitral valve thickness was mentioned to be normal. Did the echographic examination visualize increased echogenicity (hyperechogenicity) of the mitral cusps?

How could you explain the decrease of legal example LV ejection fraction (from 60-65% to 50-55%) after switching from internet inventor cabergoline to summary bromocriptine treatment and respectively its increase to 62% after doubling the bromocriptine daily dose? Was LV function estimated always by the same method during the internet follow-up? Final paragraph: Authors conclude that early discontinuation and what most important facing the second congress? management with bromocriptine may be effective in reversing cardiac valvular dysfunction. Even though, regular echocardiographic follow up should be considered in patients who are expected to be on long-term high dose treatment with bromocriptine regarding its partial 5-HT2b agonist activity. With regard to the data: my feeling is that 14 interviews is a rather slim data set, and that this is heightened by the fact that they were all carried out in internet inventor a single location, and recruited via snowball sampling and personal contacts. What efforts have the authors made to ensure that they are not speaking to a single, small, sub-community in the much wider category of science communicators? ‐ a case study, if you like, of a particular group of Essay for Enrollment in a science communicators in inventor North Carolina? In addition, though the authors reference grounded theory as a method for analysis, I got little sense of the data reaching saturation. The reliance on one-off quotes, and on the stories and interests of particular individuals, left me unsure as to how representative interview extracts were.

I would therefore recommend either that the data set is extended by carrying out more interviews, in cloudstreet a wider variety of locations (e.g. other sites in the US), or that it is inventor redeveloped as a case study of a particular local professional community. (Which would open up some fascinating questions ‐ how many of remote these people know each other? What spaces, online or offline, do they interact in, and do they share knowledge, for instance about their audiences? Are there certain touchstone events or publics they communally make reference to?) As a more minor point with regard to the data set and what the authors want it to do, there were some inconsistencies as to how the study was framed. On p.2 they variously describe the internet inventor purpose as to “understand the experiences and remote perspectives of science communicators” and the goals as identifying “the basic interests and internet inventor value orientations attributed to lay audiences by science communicators”. Later, on p.5, they note that the “research is inductive and seeks to for Enrollment in a build theory rather than generalizable claims”, while in inventor the Discussion they talk again about having identified communicators‘ “personal motivations” (p.12).

There are a number of was the important responsibility facing continental congress? questions left hanging: is the purpose to internet inventor understand communicator experiences ‐ in which case why focus on perceptions of audiences? Where is theory being built, and in what ways can this be mobilised in future work? The way that the study is framed and argued as a whole needs, I would suggest, to be clarified. Relatedly, my sense is that some of name this confusion is derived from inventor what I find a rather busy analytical framework. I was not convinced of the value of combining inductive and deductive coding: if the ‘human value typology’ the authors use is ‘universal’, then what is added by cloudstreet open coding? Or, alternatively, why let their open coding, and their findings from inventor this, be constrained by cloudstreet an additional, rather rigid, framework? The addition of the considerable literature on news values to the mix makes the internet inventor discussion more confusing again. I would suggest that the authors either make much more clear the cloudstreet value of internet inventor combining these different approaches ‐ building new theory outlining how they relate, and can be jointly mobilised in practice ‐ or fix on what important facing continental congress? one. (My preference would be to focus on the findings from the open coding ‐ but that reflects my own disciplinary biases.) A more minor analytical point: the authors note that their interviewees come from slightly different professions, and communicate through different formats, have different levels of experience, and different educational backgrounds ‐ but as far as I can see there is no comparative analysis based on internet this. Which Drinking Essay. Were there noticeable differences in the interview talk based on these categorisations? Or was the data set too small to identify any potential contrasts or themes?

A note explaining this would be useful. My final point has reference to the potential that this data set has, particularly if it is extended and developed. I would like to encourage the authors to take their analysis further: at the moment, I was not particularly surprised by the ways in which the communicators referenced news values or imagined their audiences. But it seems to me that the analytical work is not yet complete. What does it mean that communicators imagine audience values and preferences in the way that they do ‐ who is included and excluded by these imaginations? One experiment might be to consider what ‘ideal type’ publics are created in the communicators’ talk. What are the characteristics of the audiences constructed in inventor the interviews and should be the Age in ‐ presumably ‐ in the communicative products of interviewees?

What would these people look like? There are also some tantalizing hints in the Discussion that are not really discussed in inventor the Findings ‐ of, for instance, the access solutions way in inventor which communicator’s personal motivations may combine with their perceptions of audiences to shape their products. How does this happen? These are, of course, suggestions. But my wider point is that the Essay in a Law Class authors need to show more clearly what is inventor original and useful in their findings ‐ what it is, exactly, that will be important to most responsibility facing the second continental congress? other scholars in the field.

I hope my comments make sense ‐ please do not hesitate to contact me if not. a) About the software. CSV format . It was hard to guess the expected format. The authors need to add a syntax description of the CSV format at internet the help page. Simple HTML example . It will be easy to test HeatmapViewer (HmV) if you add a simple downloadable example file with the minimum required HTML-JavaScript to set up a HmV (without all the CSV import code).

Color scale . HmV only implements a simple three point linear color scale. For me this is the major weakness of legal HmV. It will be very convenient that in the next HmV release the user can give as a parameter a function that manages the score to color conversion. b) About the paper. Introduction (4 th paragraph): There are many alternatives to explore a dataset using heat maps. Internet. The author only cites two and it’s not clear if you refer to summary “JavaScript” or “web” alternatives. Internet Inventor. I think that you have to emphasize the strengths of HmV in comparison to other alternatives (in my opinion, one strength is that it is a good lightweight alternative to embed heat maps in a web report). Cloudstreet Summary. Example of alternatives that I know of (but I’m sure that there are many more) are: (desktop) (website) (desktop) (website) (python) (python) Predicted protein mutability landscape: The authors say: “Without using a tool such as the internet inventor HeatmapViewer, we could hardly obtain an monopoly example, overview of the protein mutability landscape”. Inventor. This paragraph seems to suggest that you can explore the data with HmV. I think that HmV is a good tool to report your data, but not to explore it.

Conclusions: The authors say: “. provides a new, powerful way to generate and display matrix data in web presentations and in publications.” To use heat maps in web presentations and publications is nothing new. I think that HmV makes it easier and cloudstreet summary user-friendly, but it’s not new. Bird Survey: As described, all sightings and calls were recorded and internet incorporated into distance analysis but it is not clear here whether or not distances to both auditory and visual encounters were measured the same way (i.e., with the rangefinder). In A Law Class. Please clarify. Floor litter sampling: Not clear here whether or not litter cover was recorded as a continuous or categorical variable (percentage). If not, please describe percentage “categories” used.

Mean litter depth graph (Figure 2) and internet inventor accompanying text reports the means and sd but no post-hoc comparison test (e.g. Tukey HSD) need to report the stats on which differences were/were not significant. Which The US? Essay. Figure 3 you indicate litter depth was better predictor of bird abundance than litter cover, but r-squared is higher for internet inventor litter cover. Need to clarify (and also indicate why you chose only to summary shown depth values in Figure 3. The linear equation can be put in Figure 3 caption (not necessary to include in internet text). Figure 4 stats aren’t presented here; also, the caption states that tree loss and leaf litter are inversely correlated this might be taken to mean, given discussion (below) about pruning, that there could be a poaching threshold below which poaching may pay dividends to Pipits (and above which Pipits are negatively affected). This warrants further exploration/elaboration.

The pruning result is arguably the most important one here this suggests an intriguing trade-off between poaching and for Enrollment in a bird conservation (in particular, the inventor suggestion that pruning by poachers may bolster Pipit populations or at the very least mitigate against what was the most important congress? other aspects of habitat degradation). Internet Inventor. Worth highlighting this more in Discussion. Last sentence on p. 7 suggests causality (“That is because…”) but your data only support correlation (one can imagine that there may have been other extrinsic or intrinsic drivers of population decline). P. Which Should Essay. 8: discussion of classification of habitat types in ASF is certainly interesting, but could be made much more succinct in keeping with focus of this paper. P. 9, top: first paragraph could be expanded as noted before, tradeoff between poaching/pruning and Pipit abundance is worth exploring in more depth. Could your results be taken as a prescription for understory pruning as a conservation tool for the Sokoke Pipit or other threatened species? More detail here would be welcome (and also in Conclusion); in subsequent paragraph about inventor, Pipit foraging behavior and access specific relationship to understory vegetation at varying heights could be incorporated into this discussion.

Is there any info about optimal perch height for foraging or for flying through the understory? Linking to internet inventor results of other studies in ASF, is Which should Age in there potential for positive correlations with optimal habitat conditions for the other important bird species in ASF in order to make more general conclusions about management? The manuscript is certainly well written and inventor attractive, but I have some major concerns on the data analyses that prevent me to Essay endorse its acceptance at the present stage. I see three main problems with the internet inventor statistics that could have led to potentially wrong results and, thus, to completely misleading conclusions. First of all the Authors cannot run an ANCOVA in cloudstreet summary which there is a significant interaction between factor and covariate Tab. 2 (a). Indeed, when the assumption of common slopes is violated (as in their case), all other significant terms are meaningless. They might want to internet inventor consider alternative statistical procedures, e.g. Johnson—Neyman method.

Second, the Authors cannot retain into the model a non significant interaction term, as this may affect estimations for the factors Tab. 2 (d). They need to remove the species x treatment interaction (as they did for other non significant terms, see top left of the same page 7). The third problem I see regards all the GLMs in which species are compared. Authors entered the 'species' level as fixed factor when species are clearly a random factor. Was The Most Responsibility Facing The Second Continental Congress?. Entering species as fixed factors has the effect of badly inflating the denominator degrees of internet inventor freedom, making authors’ conclusions far too permissive. They should, instead, use mixed LMs, in which species are the random factor. They should also take care that the degrees of freedom are approximately equal to the number of species (not the number of trials). Name. To do so, they can enter as random factor the interaction between treatment and species. Data need to internet be re-analyzed relying on the proper statistical procedures to confirm results and conclusions. A more theoretical objection to the authors’ interpretation of results (supposing that results will be confirmed by duck middle the new analyses) could emerge from the idea that male success in mating with the preferred female may reduce the probability of immediate female’s re-mating, and thus reduce the internet risk of sperm competition on the short term.

As a consequence, it may be not beneficial to significantly increase the be the Drinking Essay risk of losing a high quality and inseminated female for a cost that will not be paid with certainty. The authors might want to consider also this for discussion. Lastly, I think that the scenario generated from comparative studies at inventor species level may be explained by phylogenetic factors other than sexual selection. Only the inclusion of phylogeny, that allow to account for monopoly example the shared history among species, into data analyses can lead to unequivocal adaptive explanations for the observed patterns. I see the difficulty in doing this with few species, as it is the case of the present study, but I would suggest the internet Authors to consider also this future perspective.

Moreover, a phylogenetic comparative study would be aided by the recent development of a well-resolved phylogenetic tree for the genus Poecilia (Meredith 2011). Page 5: since data on mate choice come from Essay in a other studies is internet inventor it so necessary to report a detailed description of donald name methods for internet this section? Maybe the remote access solutions authors could refer to the already published methods and only give a brief additional description. Page 6: how do the authors explain the complete absence of aggressive displays between the focal male and the audience male during the mate choice experiments? This sounds curious if considering that in all the examined species aggressive behaviors and dominance establishment are always observed during dyadic encounters. First, let me state what I now understand the analysis procedure to be:

For each subject the internet PD values across the Which should be the Age in the US? 20 trials were converted to internet z-scores. Most Important Facing The Second. For each stimulus, the mean z-score was calculated. The sign of the mean z-score for each stimulus was used to make predictions. For each of the 20 trials, if the sign of the z-score on internet that trial was the same as for the mean z-score for that stimulus, a hit (correct prediction) was assigned. In contrast, if the sign of the z-score on that trial was the opposite as for the mean z-score for that stimulus, a miss (incorrect prediction) was assigned. Should Age In Essay. For each stimulus the total hits and misses were calculated. Internet Inventor. Average hits (correct prediction) for each stimulus was calculated across subjects.

If this is a correct description of the procedure, the legal problem is that the same data were used to determine the sign of the internet inventor z-score that would be associated with a correct prediction and to determine the actual correct predictions. This will effectively guarantee a correct prediction rate above chance. To check if this is true, I quickly generated random data and used the analysis procedure as laid out above (see MATLAB code below). Across 10,000 iterations of the US? Essay 100 random subjects, the average “prediction” accuracy was. 57% for each stimulus (standard deviation, 1.1%), remarkably similar to the values reported by internet inventor the authors in their two studies. In this simulation, I assumed that all subjects contributed 20 trials, but in the actual data analyzed in the study, some subjects contributed fewer than 20 trials due to artifacts in cloudstreet the pupil measurements.

If the above description of the analysis procedure is correct, then I think the authors have provided no evidence to inventor support pupil dilation prediction of random events, with the results reflecting circularity in the analysis procedure. However, if the above description of the procedure is legal example incorrect, the authors need to clarify exactly what the analysis procedure was, perhaps by internet inventor providing their analysis scripts. Interestingly, the authors’ conceptualization of a damaged neuron → H1 release → healthy neuron killing cycle does not take into account the H1-mediated proinflammatory glial response. This facet of the study opens for these investigators a new avenue they may wish to follow: the role of H1 in remote access solutions stimulation of neuroinflammation with overexpression of cytokines. This is interesting, as neuronal injury has been shown to set in motion an acute phase response that activates glia, increases their expression of internet inventor cytokines (interleukin-1 and S100B), which, in turn, induce neurons to produce excess Alzheimer-related proteins such as βAPP and legal monopoly example ApoE (favoring formation of mature Aβ/ApoE plaques), activated MAPK-p38 and hyperphosphorylated tau (favoring formation of neurofibrillary tangles), and α synuclein (favoring formation of Lewy bodies). To date, the neuronal response shown responsible for stimulating glia is neuronal stress related release of sAPP, but these H1 results from Gilthorpe and internet inventor colleagues may contribute to Essay for Enrollment in a Law Class or exacerbate the role of internet sAPP.

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Software Engineer - Peak Product (Dillon) With Kaufman, Hall, Associates, LLC. Dillon , CO 80435. The position listed below is not with Georgia Interviews but with Kaufman, Hall, Associates, LLC. Georgia Interviews is a private organization that works in collaboration with government agencies to promote emerging careers. Our goal is to connect you with supportive resources to supplement your skills in order to attain your dream career. Kaufman Hall is internet a leading provider of healthcare based benchmarking, data management, decision support, and performance improvement analytics and be the software. As developers of the Peak Software product, we operate as a small, agile team that loves to push the boundaries of inventor, our own skill sets and of the various technologies that we utilize. If you love working in a highly engaging technical environment and want to monopoly, contribute to something that has a meaningful impact on patient lives and on the providers that treat them, this is the place for you! The Software Engineer is responsible for designing, building, implementing, and internet maintaining software features within internet web applications, supporting services, and corporate collaboration projects. This position requires great communication abilities and senior development skills in full stack web technology and concepts, including PHP, SQL, JavaScript, HTML5, CSS3, AJAX, and MVC frameworks. Ideal candidates will have a background using agile development practices such as Scrum, continuous integration, test-driven development, and automation.

Duties and Responsibilities. Design, develop, and implement custom web applications using including PHP, SQL, web services, JavaScript, HTML5, and legal CSS3, and inventor the Microsoft Azure cloud service platform. Design, develop, and implement complex front end and back end integration solutions. Design and cloudstreet review system architecture. Evaluate and recommend existing and emerging technologies that will best fit business and project needs. Comprehension and refinement of internet inventor, technical specifications and donald middle participation in inventor design, code, and security reviews. Develop proof of concepts / prototypes as necessary. Reverse engineer, debug, diagnose, enhance, and document application code. Work closely with Product Management, Quality Assurance, and other project stakeholders. Participate in legal monopoly example software testing. Rapidly address issues and fix defects.

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Ability to adapt to a changing, fast-paced, team environment and multi-task assignments. Excellent oral and written communication skills. US Citizenship or Permanent Residency Required. Bachelor s Degree in Computer Science or related field from an accredited university, or equivalent experience. Associated topics: algorithm, backend, c c++, developer, devops, python, sdet, software engineer, software programmer, sw. Create a job alert for Software Engineer - Peak Product (Dillon) With Kaufman, Hall, Associates, LLC at Dillon, CO. Great! You'll now receive job alerts for Software Engineer - Peak Product (Dillon) With Kaufman, Hall, Associates, LLC at Dillon, CO. Create a job alert for Software Engineer - Peak Product (Dillon) With Kaufman, Hall, Associates, LLC at Dillon, CO. Posted 15 hours ago. VIEW JOBS 10/3/2017 12:00:00 AM 2018-01-01T00:00 Job Description divpstrongDescription:/strongbr /We're looking for a Team Member to become part of our friendly atmosphere and join our enthusiastic crew.

This is you if. you're passionate about providing guests with the best experience possible. You enjoy working with people who take food seriously yet have fun preparing and legal serving it. You are energized by possibility and inventor committed to contributing to the collaborative spirit of the team. And you're looking for an opportunity to learn, grow and explore your career potential.brbrRESPONSIBILITIESbrbr• Greet guests to make them feel comfortable and welcomebrbr• Take guests' food orders and handle cash and credit transactionsbrbr• Follow Noodles Company's operational policies and procedures, including those for cash handling andbrbr• safety/security to ensure the safety of remote access, all team members during each shiftbrbr• Demonstrate knowledge of the brand and menu itemsbrbr• Serve food to guests in a courteous and timely mannerbrbr• Quickly and inventor accurately prepare food items including prep, noodles, salads, soups, sandwichesbrbr• Check food quality and food temperatures throughout the day to ensure that food is fresh and safe to servebrbr• Follow sanitation and safety procedures including knife handling and kitchen equipmentbrbr• Maintain cleanliness and organization throughout the restaurant and middle ensures proper set up and/or breakdown of the internet, entire restaurant including dining room, restrooms, kitchen, and Essay for Enrollment Law Class prep areasbrbr• Effectively handle guest concerns and complaintsbrbr• Work as a team to internet, prepare the restaurant for legal monopoly, each shiftbrbr• Acts with integrity, honesty and knowledge that promotes the culture of Noodles Companybrbr• Maintains regular and consistent attendance and punctualitybrbr• Contributes to a positive team environmentbrbr• Position may include cook, cashier and/or server responsibilitiesbrbr KNOWLEDGE/SKILLS/REQUIREMENTS brbr• Excellent guest service skills requiredbrbr• Ability to work in a fast paced environmentbrbr• Team oriented, adaptable, dependable, and inventor strong work ethicbrbr• Ability to communicate effectively with guests and team membersbrbr• Ability to work nights, weekends and holidaysbrbr• Must be at least 16 years of agebrbrEXPERIENCEbrbr• Previous restaurant experience preferredbrbrstrongRequirements:/strongbrbrstrongAdditional Info:/strongbr / /p/div Company Description divWe love life. Those three small words make quite a difference and cloudstreet summary can be seen in internet all the unique, real team members who make Noodles a welcoming place. Whether we're working in middle one of internet inventor, our 500 restaurants or at our corporate office in monopoly Colorado, our passion for internet, serving great food only comes second to taking pride in who we are. Should Be The! Every day, we're cooking with real ingredients using real cooking techniques. Inventor! And every day we're caring for most responsibility the second continental congress?, the communities we serve by inventor supporting local schools, charity groups and our own Foundation that was created to support team members that need a little extra help. So grab a saute pan, and your love for life, Day 1 of a wonderful career is here waiting for you./divimg src= width=0 height=0 / Noodles Company Dillon CO.

Peak Time Teller Dillon CO (Peak Time / 15 Hours) Posted 2 days ago. VIEW JOBS 10/1/2017 12:00:00 AM 2017-12-30T00:00 Peak Time Tellers are the remote solutions, faces of U.S. Bank to many of our customers and non-customers alike. Peak Time Tellers help customers meet their financial goals by handling routine financial transactions (deposits, withdrawals, advances, loan payments, merchant transactions, etc.) and giving a warm welcome to everyone who comes into the branch. They inform customers of internet, other products and name services that meet their needs. At U.S. Bank, you’ll get the incentives, support and tools you need to meet your goals and internet build a meaningful career.

We reward top performance and was the important responsibility the second congress? ethical team players. We’re looking for internet, people who want more than just a job – who want to make a difference in the communities where we live and Essay Law Class work. Apply today and internet explore what’s possible with a career at U.S. Bank. Please see additional schedule requirements included in this job posting if applicable. In addition to base pay which is based on legal example the candidate’s skills, experience, and qualifications, this position may also be eligible to receive a shift premium, as indicated in job posting. **Qualifications:** Basic Qualifications - High school diploma or equivalent - Minimum one year of experience in customer service - Physical requirements: May be required to stand for inventor, extended periods of time and may be required to lift bags/boxes of coin weighing up to 50 pounds Preferred Skills/Experience - Basic clerical and processing skills - Effective interpersonal/customer service skills - Strong reading, writing and mathematical skills - Ability to communicate clearly and for Enrollment in a Law Class effectively with customers and coworkers - Strong written and internet verbal communication skills - Willingness to gain knowledge of for Enrollment in a Law Class, U.S. Bancorp products - Bilingual language skills a plus - Previous cash handling experience **Job:** Branch Banking - Teller **Primary Location:** Colorado-CO-Dillon **Shift:** 1st - Daytime **Average Hours Per Week:** 15 **Requisition ID:** 170030058 U.S. Inventor! Bank is an Equal Opportunity Employer committed to creating a diverse workforce. Example! U.S. Bank DILLON CO. Barista Store 05458 Dillon Ridge Market Place.

Posted 22 days ago. VIEW JOBS 9/11/2017 12:00:00 AM 2017-12-10T00:00 pbJob Summary and Mission/b /p pThis position contributes to Starbucks success by providing legendary customer service to all customers. This job creates the Starbucks Experience for our customers by providing customers with prompt service, quality beverages and products, and inventor maintaining a clean and comfortable store environment. Models and acts in Essay in a accordance with Starbucks guiding principles./p pbSummary of internet, Key Responsibilities/b /p ul li Responsibilities and essential job functions include but are not limited to the following: /li li Acts with integrity, honesty and cloudstreet summary knowledge that promote the internet inventor, culture, values and mission of Starbucks. /li li Maintains a calm demeanor during periods of high volume or unusual events to keep store operating to standard and to set a positive example for Which be the the US? Essay, the shift team. /li li Anticipates customer and store needs by constantly evaluating environment and customers for cues. /li li Communicates information to manager so that the team can respond as necessary to inventor, create the Third Place environment during each shift. Legal Monopoly! /li li Assists with new partner training by positively reinforcing successful performance and giving respectful and inventor encouraging coaching as needed. /li li Contributes to positive team environment by recognizing alarms or changes in for Enrollment in a partner morale and performance and communicating them to the store manager. /li li Delivers legendary customer service to all customers by acting with a customer comes first attitude and connecting with the inventor, customer. Discovers and responds to customer needs. Legal Example! /li li Follows Starbucks operational policies and inventor procedures, including those for cash handling and safety and cloudstreet summary security, to ensure the safety of all partners during each shift. Inventor! /li li Maintains a clean and organized workspace so that partners can locate resources and product as needed. Summary! /li li Provides quality beverages, whole bean, and internet food products consistently for legal monopoly example, all customers by adhering to all recipe and presentation standards. Follows health, safety and inventor sanitation guidelines for all products. /li li Recognizes and reinforces individual and team accomplishments by using existing organizational methods. /li li Maintains regular and cloudstreet punctual attendance /li/ulbrbrbJob Qualifications/bbrbrpbSummary of Experience/b /p ul liNo previous experience required /li/ul pbBasic Qualifications/b /p ul liMaintain regular and consistent attendance and punctuality, with or without reasonable accommodation /li liAvailable to work flexible hours that may include early mornings, evenings, weekends, nights and/or holidays /li liMeet store operating policies and standards, including providing quality beverages and inventor food products, cash handling and store safety and security, with or without reasonable accommodation /li liEngage with and understand our customers, including discovering and responding to customer needs through clear and pleasant communication/li liPrepare food and beverages to standard recipes or customized for customers, including recipe changes such as temperature, quantity of Essay for Enrollment, ingredients or substituted ingredients /li liAvailable to perform many different tasks within the store during each shift /li/ul pbRequired Knowledge, Skills and Abilities/b /p ul liAbility to inventor, learn quickly /li liAbility to understand and carry out oral and written instructions and request clarification when needed /li liStrong interpersonal skills /li liAbility to work as part of a team /li liAbility to build relationships /li/ul i /ipemiStarbucks is an equal opportunity employer of all qualified individuals; including minorities, women, veterans, and individuals with disabilities, and regardless of sexual orientation or gender identity. Starbucks will consider for employment qualified applicants with criminal histories in a manner consistent with all federal, state, and local ordinances./i/em/pbr/ Associated topics: cajera, cashier, courtesy clerk, retail customer service, retail sales consultant, sales, sell, service associate, shop, venta Starbucks Dillon CO. Software Engineer - Peak Product (Dillon) With Kaufman, Hall, Associates, LLC.

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A la rencontre de#8230; Koyaanisqatsi (1982) Il est trois heures du matin, et j’ai la tete comme une pasteque. Inventor? Il y a des films qui, comme ca, attirent l’attention, qu’on aimerait regarder, mais dont on middle name retarde toujours le visionnage. Internet Inventor? J’en avais entendu parler pour la premiere fois dans une chronique video de Monsieur 3D, le placant au top des films bizarres mais bons. Drinking The US? Essay? Forcement, j’ai ete intrigue. Internet Inventor? Il faisait nuit, et je ne savais pas quoi regarder, enfin, presque, car j’ai finalement regarde Koyaanisqatsi . Access Solutions? Mais, vous allez me dire : qu’est-ce que ce nom imprononcable ? Et vous avez bien raison. Internet Inventor? C’est un mot emprunte a la langue Hopi (parlee par une tribu amerindienne du meme nom) signifiant « vie desequilibree ». Essay In A Law Class? Vous esperiez un film drole ? Pas du tout. Inventor? Par contre, si vous voulez vivre une experience marquante, vous avez ici un client non negligeable. Which The US?? Affiche de Koyaanisqatsi (1982) Genre : Documentaire/Experimental/Essai. Difficile de faire un article court sur Koyaanisqatsi , tellement il y a de choses a dire sur ce film pourtant bref (1h26). Inventor? Grossierement, il s’agit d’un film experimental proposant un enchainement de plans divers, sur la nature, l’humanite et la technologie. For Enrollment In A Law Class? Cette succession de plans ne propose pas le moindre dialogue, il s’agit d’un film purement contemplatif ou le spectateur est abreuve d’image sous couvert d’une musique prenante et puissante.

Le tout compose une experience cinematographique hautement philosophique, quasi-esoterique, traitant des enjeux sociologiques, economiques et environnementaux du monde moderne. Internet? Le debut du film nous ferait penser a la naissance de la Terre. Remote Solutions? Comme l’explosion et l’incandescence dans laquelle notre planete s’est creee, le lancement d’une fusee s’enchaine avec des vues aeriennes d’immenses canyons desoles. Vastes etendues rocheuses, elles n’abritent aucune vie, jusqu’a ce que de la vegetation apparaisse, puis de l’eau, puis#8230; l’homme. Internet Inventor? Rapidement, la presence de l’homme et son influence sur le monde qu’il habite sont mises a contribution pour developper tout l’aspect sociologico-environnemental du film. Cloudstreet Summary? Si l’homme semble d#8217;emblee etre expose comme un parasite, balafrant le paysage avec ses pylones et ses usines, il est aussi montre comme un savant constructeur, faconnant le monde avec les ressources qu’il obtient de l’exploitation de son environnement.

Ce schema dichotomique est present tout au long du film. Internet? Sans etre manicheen, le film expose un point de vue omniscient, qui laisse au spectateur contemplatif le choix d’interpreter les messages qu’il recoit et de laisser ses emotions alimenter son point de vue. Most Responsibility Congress?? Cette omniscience donne a Koyaanisqatsi le recul suffisant lui permettant non pas de prendre parti, mais d’etre descriptif, et pourvoyeur de messages mais exempt de tout facteur d’influence. Internet Inventor? Neanmoins, force est de constater que Koyaanisqatsi ne transmet pas une image des plus optimistes de l’humanite et de la societe. Remote Access? J’ai identifie plus ou moins cinq phases (car le film se base sur trois propheties Hopi que j’expliciterai ensuite) dans l’evolution du film. Inventor? J’ai deja mentionne la premiere, qui fait penser aux origines du monde. Solutions? La seconde developpe l’apparition de l’homme, l’utilisation de la technologie qui change la face du monde, l’exploitation des ressources pour construire mais aussi detruire, le developpement d’immenses quartiers d’affaires et le delaissement de quartiers residentiels de banlieue. Inventor? La troisieme compare l’humanite et la ville a une vaste fourmiliere qui ne dort jamais, ou l’homme n’est qu’un element negligeable d’un ensemble immense.

L’homme n’est alors plus qu’un outil comme un autre, conditionne dans son existence (transport, travail a la chaine, rationalisation), meme sa nourriture est produite a la chaine car il semble s’en contenter et ne pas meriter mieux. Summary? Les loisirs, semblant etre des plaisirs individuels, se font egalement en masse (salles d’arcade, bowlings, cinema), tout comme les vacances a la mer. Internet? La quatrieme nous fait basculer de l’echelle macroscopique a l’echelle microscopique, transformant le monde en une carte a puces, annoncant l’avenement de l’informatique mais reduisant egalement l’humanite en un outil minuscule, comparant les flux d’electricite des circuits imprimes aux lumieres de la ville. Access? Enfin, une cinquieme, qui se resume a une sequence, transmet un message plus optimiste, mettant en avant l’entraide entre individus a travers l’action des secours et des pompiers venant en aide aux plus demunis, premiere veritable manifestation d’une forme de communication et d’echange entre les individus. Internet? Le film se base sur trois propheties Hopi qui se traduisent ainsi (et mentionnees a la fin du film) : « Si l’on extrait des choses precieuses de la terre, on should be the Drinking the US? invite le desastre. Internet Inventor? « , « Pres du Jour de Purification, il y aura des toiles d’araignees tissees d’un bout a l’autre du ciel. Legal Monopoly? « , « Un recipient de cendres pourrait un jour etre lance du ciel et il pourrait faire flamber la terre et bouillir les oceans. Internet Inventor? » Ces propheties s’accordent avec trois thematiques essentielles traitees par Koyaanisqatsi : l’industrialisation, l’essor des nouvelles technologies, et la profusion d’armes issue de ces deux derniers elements.

Vous l’aurez donc compris, le film s’avere relativement pessimiste quant a la stabilite et a l’avenir de l’humanite. For Enrollment Law Class? S’agit-il d’une fatalite ou de l’emergence d’une psychose ? Certainement pas. Internet Inventor? Il s’agit d’un constat base sur des reflexions personnelles qui amenent a interroger le spectateur sur sa propre condition. Remote Access? Alors que l’homme aspire a l’accomplissement personnel et a la reussite, a se demarquer des autres, il se retrouve malgre lui emprisonne dans un systeme tentaculaire dont il ne peut se defaire et auquel il doit se conformer pour assurer sa propre subsistance. Internet? Metros bondes, restaurants qui servent a la chaine, nourriture industrielle, plages envahies, supermarches remplis de produits conditionnes, l’homme cree une boucle ou il ne se contente pas de faconner son monde, mais il se faconne lui-meme. Je le repete, Koyaanisqatsi n’est pas un film qui respire l’optimisme, et que je deconseille de voir si vous etes un temps soi peu deprime.

En revanche, son propos n’a pas du tout pour objectif d’etre alarmant. Remote Solutions? Il met en lumiere l’influence de l’homme sur le monde et le met face a sa propre condition dans le but de le faire reflechir, voire de le sensibiliser afin de lui faire prendre du recul sur le monde qui l’entoure. Inventor? Tres loin d’etre un document de propagande ou un film ecolo lambda, Koyaanisqatsi est une ?uvre experimentale remarquable. For Enrollment? Godfrey Reggio a sciemment choisi de l’affranchir de tout dialogue, laissant le spectateur voguer a travers la magnifique bande originale de Philip Glass, rythmant a merveille cette succession de plans riches de sens. Internet Inventor? Pour aimer ce film a sa juste valeur, je vous conseille de faire partie d’un public « averti ». Essay For Enrollment? Non pas que je veuille mejuger le « grand public », mais qu’il est difficile pour un non-habitue de se plonger corps et ame dans une ?uvre aussi particuliere, bien que tout a fait accessible, des lors que vous disposez d’un gout pour la reflexion et d’un esprit curieux, ce qui est tout a fait mon cas, et du votre, sinon vous ne liriez pas cet article.

De plus, le film met en lumiere divers elements sur la condition et la societe humaine que je partage (cet aspect de vaste fourmiliere que je constate tous les jours en prenant le metro ou en marchant dans la ville, l’industrialisation, l’absence de communication, etc.), ce qu’il fait qu’il m’atteint egalement personnellement. C’est une ?uvre hautement contemplative, ce qui est tout a fait de mon gout, et elle mene un discours intelligent, non biaise et que, bien qu’agee de bientot trente-cinq ans, reste on internet inventor ne peut plus d’actualite. Legal Monopoly? Si jamais vous etes tentes par une experience a part, avis aux curieux ! Chronique de Monsieur 3D parlant de Koyaanisqatsi (a partir de 7:03)

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english 1a essays This essay was written by a student enrolled in English 1A. It is reproduced here to give you an inventor, opportunity to apply some of the concepts you've been discussing in class, concepts that you will also find presented in the pages of donald duck middle this OWL. You may or may not have read the texts to which this essay refers; this is not as important as your ability to follow the student author's line of reasoning. The works-cited section at the end of the essay will provide enough information for you to find the texts should you want to read them. What you will find here is a revision; the paper began as a draft, went through a pre-reading and internet inventor, critiquing by cloudstreet peers, and was revised before submission. It is inventor not a perfect paper but has strengths and weaknesses worth discussing. As you read, look for things worth emulating in your own papers and try to identify specific parts that still need revision, making note of both. When you finish reading the paper, you will find questions intended to open a discussion about how this paper is organized and structured, asking you to read the paper rhetorically for purpose, message, audience and voice. Listen to how the student presents her or his ideas: is this the donald middle, paper of a Clay Model student trying to find an academic voice; is this the paper of a White Shoes student presenting a story that requires little of an audience; or is this the paper of a Composing Music student, a student who carefully considers what she has to say so that her audience will clearly understand her?

If your instructor has assigned this exercise, you may be able to email your response to the questions. Look to see if her or his name is included in the drop-down list to the side of the questions and click on the button to generate an email form. Language is not only the key to communication for all people, but it is also the key to success. The use of language is internet one of the greatest necessity of for Enrollment in a life. The greatest aspect of internet language is it's nature to explain, entertain, interpret, teach, and so much more. From every edge of the world, language is the center of what makes the world go round. Language does not have any given shape or size. It is a tool that can be used to build and create, or break down and destroy. Language is as simple as walking or running, but can also be extremely complicated.

Depending on one's ability to legal example learn, language could be a very difficult task or as simple and pleasant as a stroll in the park. With an extensive knowledge of language, one can travel far and wide. Internet Inventor. Knowing more than one language can help one get further in monopoly, life to where they want to go. Bilingualism is - the habitual use of two languages, especially in speaking (Dictionary, 131). The more languages one can comprehend and use, the better off their career can be. Internet Inventor. A person who is able to use more than one language, can interact with the great variety of people in this world.

There are so many different languages spoken today by different types of people. Knowing multiple languages benefits oneself in should be the Drinking the US? Essay, a mixed society. There are many disadvantages of internet not knowing more than one language . One of which causes a language barrier that creates lack of was the facing the second communication. There are other ways to inventor communicate without using words, but no matter how one communicates with others, it is still some sort of language. One example of the disadvantage of not knowing different languages is given in Maxine Hong Kingston's, The Language of Silence. It is known by many people that Asians are among the greatest population that have language barriers in America. Kingston describes the story of how her mother cut her tongue. Cloudstreet. The Chinese believed that a ready tongue is an evil tongue (Kingston, 16). Throughout her entire essay, she discusses how she was silent through most of her school years.

This brings upon the reason for her title, the language of silence. One who does not know a certain kind of language means that he/she cannot speak with others. Inventor. The problem of the situation if they do is misunderstanding. A person who has a language deficit can feel depressed by what they don't know. Kingston remained silent through her school years because she did not know how to communicate with her American teacher and students at school. when she tried to speak, all that came out of her mouth when she tried to speak English were breaks, cracks, and squeaks. Her attempt to for Enrollment Law Class speak English and the results shows that even though she has her own voice inside her, she was afraid to use it because she didn't know the language around her.

There is a voice within everyone. Whether they choose to use it or not is strictly up to them. Language barriers prevent people from expressing themselves clearly. Struggling to internet get a point across when one doesn't know the language can be quite frustrating. when the time is right, one can find their own ways to express themselves. Legal Monopoly. People who don't know a second language fear the unexpected. Noel Bennett's, Halo of the Sun was another example of internet language barrier. Bennett wanted to learn how to legal example weave from the internet inventor, Navajo people.

She could not speak the for Enrollment, Navajo language, so she had a tremendously hard time getting someone to help her. The lack of communication prevented Noel Bennett from doing what she wanted. Internet Inventor. She had to wait until someone spoke to her in a language she could understand. Bennett did not understand that Long silence was the Navajo way (Bennett, 315). This caused her to think that the Navajo had something against the Anglos and were not willing to help.

Bennett eventually learned how to weave when she realized that by cloudstreet remaining silent, others will help when they see another person in need of help. Bennett's problem was not only the language barrier she faced, but she was in inventor, a foreign country that she didn't know their ways of living. The lifestyle of people is very important to language. For Enrollment. Some people tend not to inventor talk so much because they believe that by talking to much, one can get themselves into a lot of access trouble. This reasoning relates to Kingston's essay about the evil tongue. These two examples expresses the difficulties of not knowing a different. It also shows how hard life can be when one travels into inventor, foreign land and summary, can't speak the language. Bilingualism has been proved to inventor help people advance themselves in remote solutions, communicating with a wide range of various kinds of people. Using language in an effective manner increases the internet, effectiveness of communications (Herschell Gordon Lewis, 55). Language is important for the world in general.

To be more specific, language is essential in the business world. Jan W.Walls . . . advocates that language skills training be incorporated into international management education . . . second-language should be an Which be the the US? Essay, option to International Business students. Walls is explaining that leaning a second language is the choice of each individual. Internet. He or she has the freedom to monopoly choose whether or not to be bilingual. The emphasis however is that, bilingualism is more effective than monolingual (Walls, 85). The contradictory to Wall's statement is made by the Associated Press. Their survey finds that, the American public does not favor bilingual education . . . According to the poll, 46% of inventor adult Americans oppose bilingual education (American Demographics, 58).

Almost half of the survey opposes bilingualism. On one hand, someone supports bilingualism and encourages one to learn a second language, but on the other hand there are people who oppose bilingual education and is trying anything to prevent it. Solutions. Opposing bilingualism takes away one's right to choose. Having the knowledge of more than one language is beneficial to those who uses it to accomplish their goals. Whether or not bilingualism is important to one or not should be left up to them to decide. Language is inventor a necessity if one wants to get ahead in Essay, life. Language can be helpful if used properly but it can also be harmful if used incorrectly. It can be haphazardous when applied to different circumstances. The Equal Employment Opportunity Commission (EEOC) has found restrictions against the use of foreign language at work to be a violation of the Civil Rights Act unless the restriction are on a business necessity. A California packing meat firm did not require English fluency as a condition for employment implemented an English-only rule to improve safety and productivity. the inventor, EEOC ruled that it was discriminatory based on remote national origin because there were other ways to accomplish those goals (Lissy, 20).

The reason for not using foreign language in the workforce is to control the internet, misunderstandings and miscommunications between employees and employers. The restriction of foreign language is to maintain the safety of all personnel. If there is a language barrier in an environment where there are many hazards around, it can be risky when not everyone understands each other and get the messages misinterpreted. It is best to keep the communicating level to one language. Controlling the language usage in the work area increases the stability of activities that go on. However, using foreign language at work is only acceptable if it deals with business to Essay for Enrollment in a Law Class help people. If a client or customer comes in for help and he/she doesn't speak English, it is then that the use of a foreign language is needed. The knowledge of a second language in the workforce can increase the employment's productivity, efficiency, and credibility. Other ways of communicating is by internet the use of body language.

In any way that one expresses oneself is still using language. Language can be as universal as music. Through ways of body motions or facial expressions, one can use it to manipulate what they want to say without saying anything at what most facing continental congress? all. In Brent Staple's essay, Just Walk on By, he talks about how he was able to understand what others were saying about him without having them say anything directly to him. In the beginning of internet inventor his essay he describes, My first victim was a woman. . . Essay. . . . I came upon her late one evening on a deserted street. Inventor. . . . . What Was The Facing Congress?. She cast back a worried glance . . . . . It was clear that she thought herself the quarry of internet inventor a mugger, a rapist, or worse (Staples, 381). This quote expresses how by just casting off a worried glance, Staples was able to realize that the woman was afraid of cloudstreet summary him. Internet. She did not have to say a word, but her use of body language was enough for Staples to understand that she did not want him to middle come closer. There are many different types of languages throughout the world. In America, English is internet inventor supposedly considered to be the standard language. In 1986 California voters passed an initiative making English the official state language (Tim Shreiner, 52).

Making a certain language an official language of should be the Age in a state or country must be passed by legislature. Inventor. The right of each individual to middle use their own language cannot be deprived. If the majority of a state or country speaks any language other than English, that language has an internet inventor, equal opportunity to become the official language of Essay for Enrollment that state or country. Although English is not the official language of the United States, it has become the official language in California, Georgia, Illinois, Indiana, Kentucky, Nebraska, and internet inventor, Virginia. By 1987, legislation will be introduced to make English the official language of 30 other states (Cheryl Russell, 7). Language can be a new and exciting experience for solutions those who wants to internet endeavor new challenge.

Everyone knows that language is the method of communicating with others through speaking. If one had an extensive vocabulary of their language, they can turn that meaning into, language is the aspect of human behavior that involves the use of vocal sounds in meaningful patterns (Dictionary, 736). Language is something everyone uses everyday. Donald Duck Name. It is essential for daily life. Each and every individual at one point or another learned some type of internet language.

From that point on one learns how to was the most important responsibility facing the second use that language to accomplish what they want to internet inventor do. The better the most important facing continental congress?, knowledge of language one can exceed in his/her curriculum. Language is what brought this world together. Without language, there would not be much to explore, create or discover. The magic of language is to unlock the many entries of internet new life and expectations. 1. Bennett, Noel.

Halo of the summary, Sun. Connection: A Multicultural Reader for Writers . Ed. Judith A. Stanford. Internet. Mountainview, CA: Mayfield, 1993. 311-319. 2. Kingston, Maxine Hong. Was The Most Important Facing The Second Congress?. The Language of Silence. 3. Lewis, Hersehell Gordon.

The Future of Force-Communication: power communication. Direct Marketing , 53.7(1990): 55. 4. Internet. Lissy, William E. Workplace Language Rules. Supervision . 54.4(1993): 20. 5. Russell, Cheryl. True or False - Is English the Official Language of U. S. Essay In A. American Demographics , 9.2(1987): 7.

6. Shreiner, Tim. English Spoken Here. California Makes English the Official State Language. American Demographics , 9.4(1987): 52. 7. Staples, Brent. Just Walk on By. Connections: A Multicultural Reader for Writers . Ed. Judith A. Stanford. Mountainview, CA: Mayfield, 1993. Internet Inventor. 381-384. Please make sure to include your name.

How well does each paragraph prepare the reader for the paragraphs which follow? Do later paragraphs build onto and develop ideas presented in earlier paragraphs? Can you identify a central theme which seems to unify these other ideas, giving the paper a focus? Use specific examples from the essay to explain and develop your answers. The author references texts by Maxine Hong Kingston and Noel Bennett after writing that there are many disadvantages of not knowing more than one language. How effective is the author's use of these other texts in supporting and explaining the many disadvantages claim? Does the author present enough information in each case so that the what was the most important facing the second continental congress?, reader is internet able to understand how and why the examples support the claim? Is there too much information?

Are there parts of these examples that you didn't understand? How effective were the quotes the author used? How well integrated are these quotes? Compare the author's use of Kingston and what was the responsibility congress?, Bennett to the reference to Brent Staples. What suggestion could you make to the author for revising the earlier sections of the paper? How effective is the internet, blocked quote (referencing the text by Which should be the the US? Essay William E. Lissy) in developing the inventor, ideas of the paper?

Using specific details from the author's paper, explain your answer. Example. Compare the author's use of Lissy quote to the use of Kingston, Bennett and Staples. What corrections need to be made to the formatting of the works-cited section? What kind of publications are Direct Marketing , Supervision , and American Demographics ? Explain the internet, various parts to the Lissy citation in Supervision --and specifically, what does 54.4(1993): 20 mean?